Results of Japan Newborn Screening Proficiency Testing

Neonatal Screening Centers in Taiwan

 Survey No.2018Q1


     I. Routine Screening Items in Taiwan

 

Assay ItemTSH

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

19.29 (P)

-

-

-

-

-

-

-

9.0

μU/ml

AutoDELFIA kit

Lab2

-

-

23.8 (P)

-

-

-

-

-

-

-

10

μU/ml

AutoDELFIA kit

Lab3

-

-

20.4 (P)

-

-

-

-

-

-

-

10.0

μU/ml

AutoDELFIA kit

Refer-
ence*

-

-

26.20 (P)

-

-

-

-

-

-

-

-

μU/ml

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay Item17-OHP

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

21.1 (P)

-

14.5

ng/ml

AutoDELFIA kit

Lab2

-

-

-

-

-

-

-

-

22.1 (P)

-

15

ng/ml

AutoDELFIA kit

Lab3

-

-

-

-

-

-

-

-

20.3 (P)

-

15.0

ng/ml

AutoDELFIA kit

Refer-
ence*

-

-

-

-

-

-

-

-

19.54 (P)

-

-

ng/ml

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemGal

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

15.0 (P) 15.0

mg/dl

Enzymatic (fluorescent)

Lab2

-

-

-

-

-

-

-

-

-

23.1 (P) 8

mg/dl

Enzymatic (colorimetric)

Lab3

-

-

-

-

-

-

-

-

-

15.3 (P) 12.0

mg/dl

Enzymatic (fluorescent)

Refer-
ence*

-

-

-

-

-

-

-

-

-

16.44 (P) -

mg/dl

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemPhe

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

242.44 (P)

-

-

-

-

-

110

μM

MS/MS

Lab2

-

-

-

-

270.6 (P)

-

-

-

-

-

100

μM

MS/MS

Lab3

-

-

-

-

312.6 (P)

-

-

-

-

-

90

μM

MS/MS

Refer-
ence*

-

-

-

-

303.67 (P)

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemMet

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

94.22 (P)

-

-

-

-

-

-

46.6

μM

MS/MS

Lab2

-

-

-

100.8 (P)

-

-

-

-

-

-

50

μM

MS/MS

Lab3

-

-

-

130.7 (P)

-

-

-

-

-

-

60

μM

MS/MS

Refer-
ence*

-

-

-

127.66 (P)

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemLeu

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

250

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

280

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

280

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemVal

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

300

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

250

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

250

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemC3

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

8.25 (P)

-

-

-

4.74

μM

MS/MS

Lab2

-

-

-

-

-

-

9.523 (P)

-

-

-

5.5

μM

MS/MS

Lab3

-

-

-

-

-

-

8.59 (P)

-

-

-

6.00

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

9.54 (P)

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemC5

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

1.22 (P)

-

-

-

-

-

-

-

-

0.57

μM

MS/MS

Lab2

-

1.305 (P)

-

-

-

-

-

-

-

-

0.52

μM

MS/MS

Lab3

-

1.81 (P)

-

-

-

-

-

-

-

-

0.60

μM

MS/MS

Refer-
ence*

-

1.33 (P)

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemC5DC

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

0.27

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

0.35

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

0.30

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

Assay ItemC8

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

0.56

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

0.50

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

0.50

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision


     II. Pilot Screening Items in Taiwan

Assay ItemCit

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

29.0

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

40

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

40.0

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemC0/(C16+C18)

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

124.71 (P)

-

-

35.0

-

MS/MS

Lab2

-

-

-

-

-

-

-

134.4 (P)

-

-

-

-

MS/MS

Lab3

-

-

-

-

-

-

-

134.5 (P)

-

-

40.0

-

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

106.75 (P)

-

-

-

-

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

Assay ItemC5OH

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

0.78

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

0.8

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

0.75

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemC14:1

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

0.44

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

0.8

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

0.80

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 

Assay ItemC14:1/C2

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

-

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

-

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

-

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

Assay ItemC16OH

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

0.20 (P)

-

-

-

-

-

-

-

-

-

0.18

μM

MS/MS

Lab2

0.374 (P)

-

-

-

-

-

-

-

-

-

0.15

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

0.25

μM

MS/MS

Refer-
ence*

0.17 (P)

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

Assay ItemC18OH

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

-

-

-

-

0.25

μM

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

0.5

μM

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

0.20

μM

MS/MS

Refer-
ence*

-

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

     III. Other

Assay ItemC3/C2

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

-

-

-

-

-

-

0.89 (P)

-

-

-

0.26

-

MS/MS

Lab2

-

-

-

-

-

-

-

-

-

-

-

-

MS/MS

Lab3

-

-

-

-

-

-

-

-

-

-

-

-

MS/MS

Refer-
ence*

-

-

-

-

-

-

0.83 (P)

-

-

-

- -

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

Assay ItemC18:1OH

Lab

Sample 801-1

Sample 801-2

Sample 801-3

Sample 801-4

Sample 801-5

Sample 801-6

Sample 801-7

Sample 801-8

Sample 801-9

Sample 801-10

Cut
-Off
Unit Method
/Reagent

Lab1

0.27 (P)

-

-

-

-

-

-

-

-

-

0.16

μM

MS/MS

Lab2

0.325 (P)

-

-

-

-

-

-

-

-

-

0.15

μM

MS/MS

Lab3

0.24 (P)

-

-

-

-

-

-

-

-

-

0.20

μM

MS/MS

Refer-
ence*

0.17 (P)

-

-

-

-

-

-

-

-

-

-

μM

-

* The amount added by QA center.
** The positive result assigned by the participants are indicated by red color in the table and the (P) indicates out-of-expected range (i.e. Positive) decision

 


若有任何疑問,歡迎來電(函)聯繫或指教
地 址:10699 台北郵政 26-624 號信箱  電 話:(02)2703-6080
    e-mail:  傳 真(02)2703-6070
                           
     財團法人預防醫學基金會 
          updated : 29 Mar, 2018